Twyla Chang
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The present study aims to identify if any one type of the hormonal intervention is superior in terms of the suppression of microvessel formation in the prostate. The effects of three different hormonal therapies on angiogenesis and microvascularity in rat ventral prostate were compared. Further clinical studies are warranted.. Materials and methods. There was no statistically significant difference between mean microvessel number in rat prostate tissue treated with finasteride or bicalutamide (P > coumadin medication side effects 0.05). Even though finasteride was not as effective as castration in reducing microvessel number, acyclovir its effect was equal to that of bicalutamide in terms of suppressing the angiogenesis in prostatic tissue. A group of anti-androgens acyclovir with different mechanisms of action and adverse effects have been investigated in patients with gross hematuria related to benign prostate hyperplasia; however, there is not yet any consensus about the standard management of these patients. Mean microvessel densities in the bicalutamide and finasteride groups were significantly higher than microvessel densities in the castration group (P
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